Medical Advisory Board

  • Dr. M. Mahmood Hussain, President

    Dr. Hussain is a Distinguished Professor of the State University of New York Downstate Medical Center, Brooklyn, N.Y.; the Endowed Chair of the Department of Foundations of Medicine, and the Director of the Diabetes and Obesity Research Center at New York University Long Island School of Medicine, Mineola, N.Y.

    Dr. Hussain’s laboratory focuses on the assembly and secretion of apolipoprotein B-containing lipoproteins in the liver and intestine with an emphasis on understanding different regulatory mechanisms and the structure-function of microsomal triglyceride transfer protein (MTTP). His studies focus on how the MicroRNAs, circadian rhythms and transcription factors regular MTP expression to modulate plasma lipid levels, atherosclerosis and obesity. To further the understanding of the MTP biology, he is studying its function in other tissues not involved in the lipoprotein assembly and secretion, such as pancreas, adopisde, testis and ovary.

  • Richard J. Deckelbaum, MD, CM, Vice President

    Dr. Deckelbaum is a Professor of Epidemiology and Pediatrics, Robert R. Williams Professor of Nutrition and immediate past Director of the Institute of Human Nutrition at Columbia University Irving Medical Center, New York, NY.

    The major focus of Dr. Deckelbaum’s laboratory is to determine regulatory mechanisms for cell-lipid particle interaction, and cell cholesterol and triglyceride metabolism. Integrated with these studies includes research on how different lipids, omega-3 and other free fatty acids regulate gene expression and mechanisms affecting atherogenesis, myocardial infarction and stroke. Dr. Deckelbaum has published research papers on abetalipoproteinemia, hypobetalipoproteinemia, and chylomicron retention disease and has been active in treating and establishing management programs for these conditions.

  • Cindy Bredefeld, DO, Secretary

    Dr. Bredefeld is an Endocrinologist at New York University Langone Diabetes & Endocrinology Associates-Long Island, Assistant Professor of Clinical Medicine at NYU Long Island School of Medicine, and the Director of Diabetes and Lipid Clinical Trials.

    As a board-certified lipidologist, her clinical practice focuses on the diagnosis and management of a range of lipid disorders. She regularly lectures on topics in clinical lipidology and is the principal investigator of randomized controlled clinical trials in the field. Together with other members of the Abetalipoproteinemia and Related Disorders Foundation, she is working to increase awareness and improve the quality of care for patients affected by these rare disorders.

  • Dennis D. Black, M.D.

    Dr. Black is a pediatric Gastroenterologist at the Le Bonheur Children’s Hospital, Memphis, TN. Black is the scientific director of the Children’s Foundation Research Institute (CFRI).

    As a clinician he specializes in pediatric liver diseases and was part of the team responsible for the very first living donor liver transplant in a pediatric patient in the country in 1989 at the University of Chicago. As a scientist, Black has taken a fascination to studying lipids and understanding how they are absorbed in children and neonates. He has focused on apolipoprotein A-IV and demonstrated a role for this protein in facilitating fat absorption in the neonatal small intestine.

    He was recruited in 1999 to serve as scientific director for the Children’s Foundation Research Institute. He is also vice president of Research at Le Bonheur and the J. D. Buckman endowed professor of pediatrics and physiology at the University of Tennessee Health Science Center (UTHSC).

  • Mitchell F. Brin, MD, FAAN, FANA, FAHS

    Dr. Brin is a Clinical Professor of Neurology at the University of California, Irvine, CA.

    His internship from 1979-1980 was with Icahn School of Medicine at Mount Sinai/Mount Sinai Hospital. From 1980-1983 he was a resident doctor at the New York Presbyterian Hospital (Columbia Campus) in the field of neurology. He completed a Fellowship that lasted from 1983-1986 at Columbia University Neurologic Institute that focused on movement disorders.

  • Ettie Granot

    Dr. Granot is a graduate of the Hebrew University-Hadassah Medical School in Jerusalem and Professor (Emeritus) of Pediatrics at the Faculty of Medicine of the Hebrew University , Jerusalem. Granot is a Specialist in Pediatrics, Gastroenterology , Nutrition and Hepatology.

    Prof. Granot served as Head of Pediatric Gastroenterology at the Hadassah Medical Center , Jerusalem and as Director of the Division of Pediatrics at Kaplan Medical Center , Rehovot. She currently heads the Pediatric Liver Disease Service at Kaplan Medical Center. Among her various academic positions at the Faculty of Medicine of the Hebrew University, Prof. Granot served as Chairperson of Pediatric Studies. Basic science research has focused mainly on lipoproteins and fatty acid metabolism. Other research areas include GI infectious diseases and malabsorption disorders. Prof. Granot also has an MHA degree ( Master’s in Health Administration) from Ben Gurion University.

  • Paul Biderman, Patient Liaison

    Mr. Biderman was diagnosed with Abetalipoproteinemia in 1966, prior to his first birthday. He leads an Abetalipoproteinemia Facebook group and serves as a valuable resource to other patients and their caregivers. He has been active in the patient community for more than 20 years.

  • Anna Marie McPhail